Anti-Viral Drugs for Human Adenoviruses

Anti-Viral Drugs for Human Adenoviruses

There are many stages in the development of a new drug for viral infection and such processes are even further complicated for adenovirus by the fact that there are at least 51 serotypes, forming six distinct groups (A–F), with different degree of infectivity. This review attempts to address the importance of developing pharmaceuticals for adenovirus and also review recent development in drug d...

Molecular docking study of anti-viral FDA-approved drugs as novel entry and replication Ebola viral inhibitors

Background & Objective: Because of the reported high ability of virulence and the lack of appropriate drug of Ebola virus during the last decades, many investigations have been accomplished regarding discovery and the introduction of anti-Ebola drugs. The aim of this research was the bioinformatical study of entry and replication of Ebola viral inhibition by drug repurposing. Materials & Method...

Current antiretroviral drugs for human immunodeficiency virus infection: review article

Currently, there are about 37 million people worldwide living with human immunodeficiency virus (HIV) /AIDS, with an estimated two million new cases per year globally. According to estimates from the World Health Organization (WHO), only 75% of the population with HIV know their status. Initially, HIV infection was associated with significantly increased rates of mortality and morbidity. Howeve...

construction of pseudotyped human immunodeficiency virus for evaluation of anti-hiv drugs

Anti-Angiogenic Therapeutic Drugs for Treatment of Human Cancer

One of the proposed benefits of targeted therapies is reduced toxicity and improved quality of life. The approval of a new broad family of molecularly targeted anticancer drugs represents one of the most significant recent advances in clinical oncology. The growth of solid tumors is dependent on their capacity to acquire a blood supply. Much effort has been directed towards the development of d...